Beta-Lactamase DataBase (BLDB): Structure and Function
Sequence alignment for the EBR beta-lactamase family
EBR-1
| ........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......
MKKLFSLIALIGSFAFGQIKPIQIDPINNNLFVYQTFNSFNGVEYNANGMYLVTNKGIVLFDVPWQKSQYQELNDMLQEKYNLPVIAVFATHSHDDRAGDLSFYNELNIPTYATSLTNSKLKKEGKATSKFEIELGKTYKFGNEKFVFEYFGEGHTSDNVVVWFPKYKVLNGGCLIKGADAVNLGYTGEANVVEWPKTVHKLVAKHPTIKQVIPGHDNWKATGHIENTFKLLEKK-- |
| EBR-2 | ...I.....................................D.................................I.......................................................................V.......................................................................................-- | 98.30 % |
| EBR-3 | ...I.....................S...............................................................................D.........................................V............................................A..........................................-- | 97.87 % |
| EBR-4 | .........................................................................................................D.........................................V............................................T......Q...T...K............V..............-- | 97.02 % |
| EBR-5 | ...V..FVT...T............S..SH.Y........Q.ID......F.I.D...I............TM..LVL...H.......V....E..................S.F...I...................R..K....I....Q...A..L.....................K....I.....T......Q...T...K.N...........N............--- | 82.13 % |
| EBR-6 | ...IV..LT..SV............S.R..........T.Q.....V.A.....K................T...L.EK..........V....E..........D.......SA...TI.R.................T..K....V....Q...E........................I.........IT...E.MK...S.Y...............S...........NNKN | 81.86 % |
Last updated: December 22, 2025.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu
Live statistics (since March 29th, 2025)
