Beta-Lactamase DataBase (BLDB): Structure and Function
Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Sequence alignment for the CfxA beta-lactamase family

CfxA-1
........10........20........30........40........50........60........70........80........90.......100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.
MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIGVAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTWSPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNKSQASQYVAHISAVVYSLLMQTSVKS
CfxA-2.......................................................................................................................................................................................................................................................................................................E......................... 99.69 %
CfxA-3..................................................................................................................................................................................................................................................................D....................................E......................... 99.38 %
CfxA-4..................................................................................................................................................................................................................................................................N....................................E......................... 99.38 %
CfxA-5..................................................................................................................................................................................................................................................................C....................................E......................... 99.38 %
CfxA-6.................................G......................................................................................................................................V..............................................................................................................................E......................... 99.07 %
CfxA-7...............................................................................................G.......................................................................................................................................................................................................E......................... 99.38 %
CfxA-8.......................................................................................................................................................................................K..........................W....................................................................................E......................... 99.07 %
CfxA-9..............................................................................................................................................................................................................V........................................................................................E......................... 99.38 %
CfxA-10....................................................................................................................................................................................................................................F.............................D....................................E......................... 99.07 %
CfxA-11........................................................................A..........................................................................................................................................V...................................................................................E......................... 99.07 %
A-CfxA phylogenetic tree

Last updated: April 06, 2026.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database was funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since March 29th, 2025)