Beta-Lactamase DataBase
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Beta-Lactamase DataBase

Synthetic Mutants (work in progress)

Ambler class
Protein name
Mutations
PubMed ID
DOI
PDB structures
Hydrolytic profile
B1IMP-1D81A 1578841510.1074/JBC.M414314200view
B1IMP-1D81E 1578841510.1074/JBC.M414314200view
B1IMP-1C221G 2290817110.1128/AAC.01276-12
B1IMP-1C221E 2290817110.1128/AAC.01276-12
B1IMP-1C221X 19351604
B1IMP-1N223X 2189690310.1128/AAC.00340-11
B1IMP-1N233A 1171492410.1110/ps.40884
B1IMP-1XXX 1553343510.1016/j.jmb.2004.09.074
B1IMP-1D90N 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1H28A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1H86A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1H88A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1H149A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1H210A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1C168A 1095257210.1128/AAC.44.9.2304-2309.2000
B1IMP-1N167A 1128715110.1111/j.1574-6968.2001.tb10587.x
B1IMP-1N167D 1128715110.1111/j.1574-6968.2001.tb10587.x
B1IMP-1K161R 1128715110.1111/j.1574-6968.2001.tb10587.x
B1IMP-1K161A 1128715110.1111/j.1574-6968.2001.tb10587.x
B1IMP-1K161E 1128715110.1111/j.1574-6968.2001.tb10587.x

Statistics (number of mutants): Overall (167); class A (91); subclass B1 (35); subclass B2 (3); subclass B3 (6); class C (19); class D (13).

Last updated: January 08, 2024.

If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.

The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).

Contact: contact@bldb.eu

Live statistics (since December 3rd, 2023)