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|
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Ambler class |
Protein name |
Mutations |
PubMed ID |
DOI |
PDB structures |
Hydrolytic profile |
|---|---|---|---|---|---|---|
| A | PenP | E166A | 8433965 | 10.1093/PROTEIN/6.1.11 | ||
| A | PenP | E166C | 21705325 | 10.1074/JBC.M110.198895 | ||
| A | PenP | E166S | 25020031 | 10.1021/BI401609H | ||
| A | PenP | W210F W229F W251F | 22496053 | 10.1002/PRO.2076 |
Statistics (number of mutants): Overall (167); class A (91); subclass B1 (35); subclass B2 (3); subclass B3 (6); class C (19); class D (13).
Last updated: January 08, 2024.
If you use BLDB please cite: Naas, T.; Oueslati, S.; Bonnin, R. A.; Dabos, M. L.; Zavala, A.; Dortet, L.; Retailleau, P.; Iorga, B. I., Beta-Lactamase DataBase (BLDB) – Structure and Function. J. Enzyme Inhib. Med. Chem. 2017, 32, 917-919.
The development of the BLDB database is funded in part by the JPIAMR transnational project DesInMBL, the Région Ile-de-France (DIM Malinf) and the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT).
Contact: contact@bldb.eu